Clin Surg | Volume 8, Issue 1 | Research Article | Open Access

Metastatic Tumors have Become the Most Important Entity in Parotid Gland Cancer

Franzen AM1,2*

1Department of Otorhinolaryngology, Head and Neck Surgery, Brandenburg Medical School, University Medical Centre Ruppin Brandenburg, Germany
2Joint Faculty of the University of Potsdam, Brandenburg University of Technology Cottbus-Senftenberg and Brandenburg Medical School, Germany

*Correspondance to: Franzen AM 

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Aim: Lymphatic tissue enclosed in the parenchyma is the precondition for metastases to the parotid gland. Significance and clinical parameters of metastatic tumors are presented. Methods: The clinical data of 837 patients over a period of 40 years who received a parotidectomy for a tumor disease are analyzed. Two 20 years intervals are compared. Results: Of those, 144 tumors were malignant (17.2%) and 72 were metastases. The proportion of metastases was 24.4% in the first two decades and 61.6% in the second. Metastatic parotid tumor affected male patients in 75% with a mean age of 71.1 (23 and 93 years). At 81.8% metastatic tumors were squamous cell carcinoma. Metastatic tumors were in 51 cases cutaneous tumors of the head and neck, in 8 cases carcinoma of the oral cavity or pharynx and in 4 of the outer ear canals, in 6 cases the primary tumor was located below the clavicle and another 4 cases were diagnosed as CUP syndromes. Discussion: Metastatic tumors have become the most important entity in malignant parotid tumors of our patients. Indications of a metastatic disease are older age, male sex, actinically damaged skin, histological findings and tumor diseases, in particular skin carcinomas, in history. Conclusion: Distinguishing between glandular primary and parotid metastasis is an essential precondition for stratifying risk, planning treatment and aftercare in malignant parotid neoplasms.


Franzen AM. Metastatic Tumors have Become the Most Important Entity in Parotid Gland Cancer. Clin Surg. 2023; 8: 3622..

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