Grégoire Cousin1,4, Roxana Botea2,4, François Labaste3,4, Abdulrahman Aljuayli1,4, Christophe Cron1,4, Etienne Grunenwald1,4, Damien Eyharts2,4, Yoan Lavie-Badie2,4, Bertrand Marcheix1,4 and Jean Porterie1,4*
1Department of Cardiac Surgery, Rangueil University Hospital, France
2Department of Cardiology, Rangueil University Hospital, France
3Department of Anesthesiology, Rangueil University Hospital, France
4Heart Valve Center, Rangueil University Hospital, France
Background: Mitral Valve repair (MVr) is the first-choice surgical therapy for patients developing severe Degenerative Mitral Regurgitation (DMR). The aim of the present study is to report the midterm results of MVr using the Memo 3D semi-rigid annuloplasty prosthetic ring in patients referred for DMR. Methods: Two hundred fifty-five consecutive patients referred for severe DMR and undergoing MVr in our institution between January 2015 and December 2018 were retrospectively included. All of them underwent mitral annuloplasty with the Memo 3D prosthetic ring. Preoperative characteristics, operative data, in-hospital outcomes and one-year follow-up clinical and echocardiographic findings were analyzed. The main outcome was a composite of grade ≥ 2 recurrent Mitral Regurgitation (MR) and/or mitral valve reintervention during the first postoperative year. Results: Thirty-day rates of death, stroke, myocardial infarction and new permanent pacemaker implantation were 2.4%, 1.2%, 0.8% and 2.4%, respectively. At one-year post-repair, 99.6% of patients were in NYHA class I-II. Freedom from grade ≥ 2 recurrent MR, reintervention and the composite outcome were 96.7%, 97.3% and 94.2%, respectively. In univariate analysis, preoperative NYHA functional status (p=0.002), pulmonary hypertension (p=0.01), LVEF (p=0.04), and MR grade at discharge (p<0.0001) were significantly associated with the main composite outcome. Conclusion: Our study suggests that MVr with the Memo 3D semi-rigid prosthetic ring achieves satisfying and sustainable MV function, resulting in markedly improved functional status at oneyear follow-up in patients with severe DMR.
Cousin G, Botea R, Labaste F, Aljuayli A, Cron C, Grunenwald E, et al. Mitral Valve Repair with the Memo 3D Annuloplasty Ring in Degenerative Mitral Regurgitation. Clin Surg. 2022; 7: 3586..