Journal Basic Info
- Impact Factor: 1.995**
- H-Index: 8
- ISSN: 2474-1647
- DOI: 10.25107/2474-1647
Major Scope
- Bariatric Surgery
- Oral and Maxillofacial Surgery
- Orthopaedic Surgery
- Otolaryngology - Head and Neck Surgery
- Colon and Rectal Surgery
- Cardiovascular Surgery
- Minimally Invasive Surgery
- Surgical Oncology
Abstract
Citation: Clin Surg. 2021;6(1):3200.Research Article | Open Access
Predictive Role of Activated Leukocyte Cell Adhesion Molecule in Colon Cancer
Hamit Karayagiz1 , Umit Sekmen2* and Melih Paksoy2
1 Department of General Surgery, Acibadem Aile Hospital, Turkey 2 Department of General Surgery, Acibadem Fulya Hospital, Turkey
*Correspondance to: Umit Sekmen
PDF Full Text DOI: 10.25107/2474-1647.3200
Abstract
Aim: Colon cancer is one of the most common and deadly cancers worldwide. Activated Leukocyte Cell Adhesion Molecule (ALCAM) has been found to be associated with various malignancies. We investigated the expression of ALCAM in colon cancer patients, as well as its association with tumor size. Materials and Methods: A total of 90 people, 50 patients with stage II colon cancer and 40 healthy controls were included in the study. Serum ALCAM and Carcinoembryonic Antigen (CEA) levels were measured in both groups. Tumor size was evaluated in the patient group. Results: Circulating ALCAM levels were higher in patients with colon cancer than in the control group. Serum ALCAM levels were especially elevated in patients with larger tumor size. Conclusion: ALCAM is overexpressed in colon cancer, and these results suggest that serum ALCAM levels may have a predictive role in the prognosis of this disease.
Keywords
Activated leucocyte cell adhesion molecule; ALCAM; CD166; Colon cancer; Prognosis
Cite the article
Karayagiz H, Sekmen U, Paksoy M. Predictive Role of Activated Leukocyte Cell Adhesion Molecule in Colon Cancer. Clin Surg. 2021; 6: 3200..
