Journal Basic Info
- Impact Factor: 1.995**
- H-Index: 8
- ISSN: 2474-1647
- DOI: 10.25107/2474-1647
Major Scope
- Neurological Surgery
- Endocrine Surgery
- Thoracic Surgery
- Gastroenterological Surgery
- Obstetrics Surgery
- Gynecological Surgery
- Bariatric Surgery
- Cardiovascular Surgery
Abstract
Citation: Clin Surg. 2020;5(1):2959.Case Series | Open Access
Central Nervous Cryptococcosis and Chronic Hepatitis C: Two Case Reports and Review of the Literature
Fadi Al Akhrass1,2*, Madison Tackett S2 , Elio Mikhael1 , Sekufe Akhter1 and Shumaila NM Hanif2
Department of Infectious Diseases and Infection Prevention, Pikeville Medical Center, Kentucky, USA 2 Department of Basic Sciences, University of Pikeville, Kentucky College of Osteopathic Medicine, USA
*Correspondance to: Fadi Al Akhrass
PDF Full Text DOI: 10.25107/2474-1647.2959
Abstract
Hepatitis C Virus (HCV) could be a risk factor for neuropsychiatric illness and a predisposing factor for meningoencephalitis caused by opportunistic organisms such as Cryptococcus neoformans. Nonetheless, the association between virological cure and resolution of Brain-Blood Barrier (BBB) damage and neuroinflammation has remained unclear. Understanding this association may help develop strategies to reduce neuropsychiatric comorbidity in Chronic Hepatitis C (CHC) patients and improve outcomes in addiction medicine, specifically Medication-Assisted Therapy (MAT) retention. Cannabis may be a direct source of inoculation of Cryptococcus species and other fungi in the lungs and subsequent hematogenous dissemination.
Keywords
Blood Brain Barrier (BBB); Chronic Hepatitis C (CHC); Cryptococcal Meningitis (CM); Cerebrospinal Fluid (CSF): Hepatitis C Virus (HCV)
Cite the article
Al Akhrass F, Madison Tackett S, Mikhael E, Akhter S, Hanif SNM. Central Nervous Cryptococcosis and Chronic Hepatitis C: Two Case Reports and Review of the Literature. Clin Surg. 2020; 5: 2959..