Guo S1, Jin Y2* and Zhang L2*
1School of Basic Medical Sciences, Nanjing Medical University, China
2School of Pharmacy, Nanjing Medical University, China
Progesterone, as the main steroid hormone, is secreted by the corpus luteum and plays an important role in the menstrual cycle, pregnancy maintenance, as well as pathogenesis analysis and treatment of many diseases. To systematically review the progress of progesterone in clinical research, this paper describes the physiological role and focuses on the impacts of progesterone on (1) pregnancy outcome, (2) perimenopause, menopause and debilitating period, and (3) the other diseases (such as endometriosis, endometrial cancer and breast cancer). Progesterone's widespread and critical role in the body has proven to be of constant clinical interest and it gives future perspectives on the potential of this hormone in clinical medicine.
Guo S, Jin Y, Zhang L. Progress in Clinical Studies of Progesterone: A Review. Clin Surg. 2022; 7: 3546..