Jia X1, Ma KX2, Dong B2 and Zhang RX2*
1The First Operating Room, The Second Hospital of Dalian Medical University, China
2Division of Hepatobiliary and Pancreatic Surgery, The Second Hospital of Dalian Medical University, China
Radio Frequency Ablation (RFA) has been used for many types of tumors, including tumors of the liver, esophagus, and rectum, among others. However, a limited number of studies have examined the use of endoscopically applied RFA (via Endoscopic Retrograde Cholangiopancreatography (ERCP)) to treat unresectable malignant biliary obstructions. Here, we describe a case of a patient who suffered from unresectable bile duct cancer with biliary strictures but had a life expectancy of more than 3 months and received endoscopically applied (ERCP-based) RFA therapy. No pancreatitis or cholecystitis was observed after the operation. The patient’s TB, DB, and IB levels slowly decreased, and his appetite recovered. Ten days after the operation, he was discharged from the hospital. The patient was followed-up after his discharge and remained alive more than 1 year after the operation. Therefore, endobiliary RFA may be a safe therapeutic option for the treatment of malignant biliary obstructions in patients who cannot tolerate surgery. However, a multicenter randomized controlled trial is required to confirm the long-term benefits of RFA.
Jia X, Ma KX, Dong B, Zhang RX. Successful Use of Endoscopically Applied Radiofrequency Ablation in the Management of Unresectable Bile Duct Cancer. Clin Surg. 2022; 7: 3537..