Risk Factors of Post-Endarterectomy Hypertension and Influence on Clinical Outcome

Dikang P1,2, Mingyang D1,3, Zhongkai Y1,2 and Xiaoming S1*

1Department of Vascular Surgery, Hebei General Hospital, China
2Graduate School of North China University of Science and Technology, China
3Graduate School of Hebei Medical University, China

^*Correspondance to: Shi Xiaoming 

 PDF  Full Text DOI: 10.25107/2474-1647.3444

Abstract

Background: Discuss the risk factors for the occurrence of PEH and their influence on the clinical outcome by observing the influence of Post-Endarterectomy Hypertension (PEH) on the outcome of Carotid Endarterectomy (CEA). Methods: A single-center retrospective cohort study was performed. The demographics, preoperative and postoperative outcomes of 140 patients receiving CEA were evaluated. Logistic regression analysis was performed to compare postoperative outcomes. Multivariate Logistic regression analysis was performed to determine the risk factors of PEH. Results: 14 of 140 patients (10%) suffered PEH. Through univariate and multivariate logistic regression analysis, it was found that preoperative mean SBP>140 mmHg and glomerular filtration rate <90 ml/min may be the risk factors of PEH. In terms of clinical outcomes, patients with PEH had longer length of stay than patients without PEH (medians were 20 and 15 days respectively; P=0.002). There was no difference in perioperative complications during hospitalization (P=0.152). During the follow-up period, there was no significant statistical difference in the relevant postoperative complications (postoperative restenosis, reperfusion edema, nerve damage, and stroke) between the patients with PEH and the patients without PEH. Conclusion: The length of stay of PEH patients increased significantly; however, among PEH patients, there was no significant difference in the adverse event rate between the perioperative period and the short-to-medium term. In addition, we concluded that preoperative mean SBP>140 mmHg and glomerular filtration rate <90 ml/min were the risk factors of PEH.

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Cite the article

Dikang P, Mingyang D, Zhongkai Y, Xiaoming S. Risk Factors of Post- Endarterectomy Hypertension and Influence on Clinical Outcome. Clin Surg. 2022; 7: 3444..