Clin Surg | Volume 7, Issue 1 | Case Report | Open Access

Metastatic Prostate Cancer Presenting as a Rapidly Increasing Gluteal Muscle Mass at an Intramuscular Injection Site

Oluwabunmi Olapade-Olaopa E1,2*, Adekola Adebayo S1,2, Ebenezer Osobu3, Mustapha Ajani4, Sheriff Ogunlayi2, Oluwadayo A Magbagbeola2, Olumide M Farinre2, Olufemi Ogunbiyi J4 and Samuel O Ogunlade5

1Department of Surgery, Division of Urology, College of Medicine, University of Ibadan, Nigeria
2University College Hospital Ibadan, Nigeria
3Department of Radiology, College of Medicine, University of Ibadan and University College Hospital, Nigeria
4Department of Pathology, College of Medicine, University of Ibadan and University College Hospital, Nigeria
5Department of Orthopedics and Trauma, University College Hospital, Nigeria

*Correspondance to: Oluwabunmi Olapade-Olaopa E 

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Abstract

Prostate cancer is the second commonest male cancer globally. However, diagnosis may be delayed or missed due to atypical presentations such as metastases to unusual sites. The axial skeleton, lymph nodes, and viscera are the common sites for prostate cancer metastasis with skeletal muscles being uncommonly affected, and until now there has been no report of metastasis to the gluteal muscles from the disease. We present the case of a 78-year-old man with no lower urinary tract symptoms who presented with a 2-year history of a right supra-gluteal mass at the site of an intramuscular injection hematoma/abscess that rapidly increased in size 5 months prior to presentation and an abnormal gait. CT and MRI scans were suggestive of a malignant mass (possibly a rhabdomyosarcoma) and enlarged multinodular prostate with bilateral lymphadenopathy. A biopsy of the gluteal mass confirmed metastatic adenocarcinoma with the colon or the prostate being possible primaries. His serum PSA was markedly elevated (3441 ng/ml) but his other tumor markers were normal. Prostate biopsies confirmed a Gleason 4+3=7 prostate cancer and ADT was commenced. He responded well and remains in good health 15 months into his treatment with a marked reduction in the size of his gluteal mass and a restoration of a normal gait. His serum PSA and Testosterone are presently 2.4 ng/ml and 0.3 mmol/L respectively.

Citation:

Oluwabunmi Olapade-Olaopa E, Adekola Adebayo S, Osobu E, Ajani M, Ogunlayi S, Magbagbeola OA, et al. Metastatic Prostate Cancer Presenting as a Rapidly Increasing Gluteal Muscle Mass at an Intramuscular Injection Site. Clin Surg. 2022; 7: 3420.

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