Badrul Alam1 , Ahsan Javed1 , Alshammari Fanar1 , Hee-Jeong Choi2 and Sang-Han Lee1*
1 School of Food Science and Biotechnology, Graduate School, Kyungpook National University, Korea 2 Food and Bio-Industry Research Institute, Kyungpook National University, KoreaFulltext PDF
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer-related deaths among women worldwide. Chemotherapeutic drugs have yielded limited anticancer activity and have not reduced the high recurrence rate. This has fueled efforts into the identification of more effective anticancer agents. A focus on natural products with potential anticancer activity exhibiting less adverse effects has led to the study of medicinal plants. This has resulted in the discovery of compounds with remarkable chemical structures exhibiting diverse biological activities. Geography and climate variations between the South Asian Association for Regional Cooperation (SAARC) countries have provided an array of environmental conditions that yield versatile plant species. These may be used for the preparation of traditional medicine and have attracted significant attention from the scientific community. In this review, we focus on the anticancer properties of twenty-five medicinal plant species and their active constituents, which grow in SAARC countries including India, Bangladesh, Pakistan, Nepal, Sri Lanka, Bhutan, the Maldives, and Afghanistan. The mechanisms of action associated with these compounds provide a glimpse of the current trends driving anticancer drug discovery, especially with respect to breast cancer.
Plant; Breast cancer; Prevention; South Asian Association for Regional Cooperation (SAARC)
Alam B, Javed A, Fanar A, Choi H-J, Lee S-H. Plant-Based Natural Products for Breast Cancer Prevention: A South Asian Association for Regional Cooperation (SAARC) Countries Perspective. Clin Surg. 2021; 6: 3047..