Journal Basic Info
- Impact Factor: 1.995**
- H-Index: 8
- ISSN: 2474-1647
- DOI: 10.25107/2474-1647
Major Scope
- Oral and Maxillofacial Surgery
- Endocrine Surgery
- Transplant Surgery
- Robotic Surgery
- Colon and Rectal Surgery
- Bariatric Surgery
- Plastic Surgery
- Cardiovascular Surgery
Abstract
Citation: Clin Surg. 2020;5(1):2926.Review Article | Open Access
Melorheostosis: A Review Article
Makgabo John Tladi*
Department of Orthopedic Surgery, Louis Pasteur Hospital, Pretoria, South Africa
*Correspondance to: Makgabo John Tladi
PDF Full Text DOI: 10.25107/2474-1647.2926
Abstract
Melorheostosis is a benign sclerosing bone disease that affects the bone and adjacent soft tissue. Although the description of the disease was made nearly a century ago, many aspects of the condition are still unknown. This condition might be an incidental finding. Patients may present with pain that could be associated with deformities. The course is still unknown and various theories have been proposed in the literature. Diagnosis is normally made using X-rays and not all patients will have classical candle wax appearance. Recently, ?dumpling on a plate sign? for both MRI and CT scans for flat bones has been suggested. Biopsy may be done if the diagnosis is in doubt but there is no definitive histological feature. Association with other conditions is not unusual and multidisciplinary team approach should be considered. The femur seems to be associated with malignancy. The condition should be part of differential diagnosis for sclerotic bone conditions. Management is normally symptomatic relive either conservative or surgical.
Keywords
Melorheostosis; Leri disease; Sclerosing bone disease; Hyperostosis; LEMD3 gene
Cite the article
Tladi MJ. Melorheostosis: A Review Article. Clin Surg. 2020; 5: 2926..