Journal Basic Info

  • Impact Factor: 1.995**
  • H-Index: 8
  • ISSN: 2474-1647
  • DOI: 10.25107/2474-1647
**Impact Factor calculated based on Google Scholar Citations. Please contact us for any more details.

Major Scope

  •  Ophthalmic Surgery
  •  Transplant Surgery
  •  Minimally Invasive Surgery
  •  Neurological Surgery
  •  Otolaryngology - Head and Neck Surgery
  •  Thoracic Surgery
  •  Obstetrics Surgery
  •  Breast Surgery

Abstract

Citation: Clin Surg. 2018;3(1):1861.Research Article | Open Access

Clinical Significance of Lipid Metabolism in Evaluating the Prognosis of Hyperlipidemic Acute Pancreatitis

Gai Ji-qin, Ni Lei, Qin Jian-min

Department of General Surgery, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China Department of General Surgery, Affiliated Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai 201805, China

*Correspondance to: Qin Jian-min 

 PDF  Full Text DOI: 10.25107/2474-1647.1861

Abstract

Objective: To investigate the correlation between serum lipid metabolic indicators and MCTSI score in hyperlipidemic acute pancreatitis.Methods: The serum lipid metabolic indicators and MCTSI scores of 97 cases of hyperlipidemic acute pancreatitis were retrospectively analyzed from Jul. 2012 to Jul. 2016. The correlation of serum lipid metabolic indicators and MCTSI score were analyzed.Results: There existed statistically significant difference of the apoA1 levels of patients among MCTSI score =2, =4, and ≥6 group, and the higher the MCTSI score was, the lower the apoA1 level was (F=10.004, P<0.01). The serum apoA1 level of hyperlipidemic acute pancreatitis patient was negatively correlated with MCTSI score(rs = -0.420, P<0.01). In the patients with lower serum apoA1 values, the number of patients whose MCTSI scores were ≥4 was significantly more than that of those whose MCTSI scores were 2(χ2 =9.343, P<0.01). But there existed no statistically significant difference of serum TG, TC, HDL-C, LDH-C, apoB and LP(A) levels among patients with MCTSI score =2, =4, and ≥6 group (F=1.358, 0.585, 0.049, 0.439, 0.228, 0.168, P>0.05). There was no correlation between the levels of serum TG, TC, HDL-C, LDL-C, apoB, and Lp(A) and MCTSI score(rs=0.014, 0.036, -0.061, -0.050, -0.008, -0.004, P>0.05).Conclusion: Serum apoA1 level is a better indicator to evaluate the severity of hyperlipidemic acute pancreatitis. There is negative correlation between severity of hyperlipidemic acute pancreatitis and serum apoA1 level.

Keywords

Hyperlipidemic acute pancreatitis; Lipid; Apolipoprotein; MCTSI

Cite the article

Ji-qin G, Lei N, Jian-min Q. Clinical Significance of Lipid Metabolism in Evaluating the Prognosis of Hyperlipidemic Acute Pancreatitis. Clin Surg. 2018; 3: 1861.

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