Clin Surg | Volume 2, Issue 1 | Research Article | Open Access

Otomycosis Treatment: Topical Drops vs. Cream � A Prospective Randomized Study

Prasun Mishra*, Sheenu Sachdeva, Maitri Kaushik and Deeksha Aggrawal

Department of ENT, Bharati Vidyapeeth Medical College, Pune, India

*Correspondance to: Prasun Mishra 

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Introduction: Otomycosis is one of the most common conditions encountered in an ENT practice. Difference of opinion does exist regarding ideal treatment modality.Aim: Compare the treatment efficacy of 1% Clotrimazole drops with 1% Clotrimazole Cream in management of otomycosis.Method: Randomized control study was performed over 3 months. Total 60 patients, clinically diagnosed with otomycosis were included in study. Patients were randomly allotted to treatment arms of either 1% Clotrimazole drops or 1% Clotrimazole cream. Improvement in symptoms of pain, pruritis and blocked sensation on one and two weeks follow up was recorded. External auditory canal was evaluated for improvement in otomycotic debris. All patients were asked the opinion about preferred modality of treatment.Results: When compared to the symptoms on day one at day 07, the change in symptoms in both the groups was significant (p<0.05). Significant difference was also noted for the improvement in otomycotic debris in both the groups. The group with cream had significantly more blocked sensation. On second week follow up, significant improvement was noted for all the symptoms and otomycotic debris. Forty five out of sixty patients preferred using cream.Conclusion: 1% topical clotrimazole and cream are equally effective in management of otomycosis.


Otomycosis; 1% Clotirmazole; Cream; Drops


Mishra P, Sachdeva S, Kaushik M, Aggrawal D. Otomycosis Treatment: Topical Drops vs. Cream � A Prospective Randomized Study. Clin Surg. 2017; 2: 1747.

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