Kinton L, Arun A*, Harmse D and Akoh JA
Department of Oesophago Gastric & General Surgery, Derriford Hospital, UKFulltext PDF
IgG4-related disease also known as inflammatory pseudotumour and include myofibroblastic tumours and plasma cell granulomas, has recently become a recognised condition. The aetiology remains unknown, with features of both allergic and autoimmune disease. We present here such a rare case and review published cases of the disease. We present a 42 year old female patient who underwent an excision of a suspected sebaceous cyst, which was confirmed as IgG4 related disease. The patient underwent a further wide local excision due to her choice, with no evidence of recurrent disease on follow up. IgG4 related disease can present in any organ, but occur mostly to the lung, biliary tract, pancreas and the salivary gland. The visceral inflammatory pseudo tumour manifest very differently to cutaneous manifestations of the disease, with only 17 cases reported in the English literature of this condition noted to affect the skin. The cutaneous disease behaves in a benign fashion with good outcomes from surgical excision with no current evidence in the literature of local recurrence. This report adds another case of cutaneous IgG4 disease to the literature and reviews previously published cases.
Kinton L, Arun A, Harmse D, Akoh JA. Igg4 Related Cutaneous Inflammatory Pseudotumour: A Rare Case and Review of the Litesrature. Clin Surg. 2016; 1: 1217.