Clin Surg | Volume 1, Issue 1 | Research Article | Open Access

Breast Cancer in Previously Lactating Women

Amer Hashim Al Ani1*, Ehab Totah2, Moaed Lumbar2, Monther Abu Reden2, Husaen Shamot2 and Awad Al Domour2

1Department of General Surgery, Sheikh Khalifa Hospital, United Arab Emirates
2Department of General Surgery, Al-Bashir Teaching Hospital, Jordan

*Correspondance to: Amer Hashim Al Ani 

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Abstract

Background: Many studies suggest that women who breast-fed had a decreased risk of developing breast cancer (ranging from 10-64%) compared to women who never breast-fed. some studies revealed that breast-feeding had no influence on the risk of developing breast cancer. Breast-feeding may be more protective against the development of premenopausal compared to postmenopausal breast cancer. Although there are a few studies that report a decrease in the risk of breast cancer after only three or more months of breast-feeding, the evidence for risk reduction becomes more consistent the longer women breast-feed. Breast cancer in previously lactating women is rarely dealt with in the medical literatures.Patients and
Methods: From January 2009 to May 2012, fifty previously lactating women with breast cancer were studied in Al Bashir teaching hospital Amman. Jordan. Their age was ranging from 27-70 years, number of their children were ranging from 3-8 with history of breast feeding for 3months to 3years.The clinical presentation, and ultrasound characteristics, mammogram findings, & histopathological criteria were examined.Results: Breast cancer in lactating women was present in right breast in 23 patients (46%), in left breast in 27 patients (54%). It was present in upper outer quadrant in 27 patients (54%), upper inner quadrant in8 patients (16 %), lower outer quadrant in 10 patients (20%), and in lower inner quadrant in 2 patients (4%). presenting symptoms were: mass in 25 patients (50%), nipple retraction in 10 patients (20%), ulceration in 5 patients (10%), nipple discharge, or skin tethering in 4 patients each (8 %), and pain in 2 patients (4%). By ultrasound 21 lesions (42%) were hypo-echoic, 19 lesions (38%) were of mixed echogenicity, 5 lesions (10%) were isoechoic & 5 lesions (10%) were hyper -echoic. By mammogram 15 lesions (30%) were radio opaque, 12 lesions (24 %) were of low opacity, and 2 lesions (4%) were radio lucent. In 4 lesions (8%) micro calcifications were present, in 3 lesions (6%) macro calcifications were present, the mass was speculated in 9 lesions (18%) & skin thickening were present in 5 patients (10%) of lesions. Forty seven lesions (94%) were ductal carcinoma, 2 lesions (4%) were lobular carcinoma, and only 1case (2%) was malignant phylloid tumor. Thirty one lesions (62%) were poorly differentiated, 19 lesions (38%) were moderately differentiated, and no well differentiated lesions were detected.Conclusion: Breast cancer in lactating women is mostly ductal carcinoma that is present as a mass in upper outer quadrant of left breast, which is hypo-echoic by ultrasound, radio opaque by mammogram and of poor differentiation. These findings need to be reviewed with a larger number of patients.

Citation:

Al Ani AH, Totah E, Lumbar M, Abu Reden M, Shamot H, Al Domour A. Breast Cancer in Previously Lactating Women. Clin Surg. 2016; 1: 1191.

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