Trend of Causes of Brain Death in Liver Graft Donors in Northern Iran; A Shift from Trauma to Cerebrovascular Events in 30 Months

AP Ebrahimi, K Tayebi Meybodi, S Hosseini, SHA Dashti and Ali Jafarian

Hepatobiliary and Liver Transplantation Research Centre, Tehran University of Medical Sciences, Iran
Tehran University of Medical Sciences, Iran
Department of General Surgery, Tehran University of Medical Sciences, Iran

^*Correspondance to: Ali Jafarian 

 PDF  Full Text DOI: 10.25107/2474-1647.1186

Abstract

Background and
Objectives: Brain dead donor’s cause of death can potentially influence function of the transplanted liver and survival of transplant recipients. The aim of this study is to assess the trend of causes of brain death in Iranian donors.Material and
Methods: Medical charts of 181 consecutive liver donors within a period of 30 months (2013 April-2015 September) were reviewed.Results: These data were classified based on donor’s cause of brain death (DCBD) into: Traumatic (n=83, 45.9%), cerebrovascular events (n=73, 40.3%) and other brain insults (n=25, 13.8%). We compared these three groups in five 6 months periods. At the first period, among 36 donors, trauma was the leading cause (n=28, 77.8%) and cerebrovascular complications was the second comprising 13.9% causes of brain death. Trauma as a cause of brain death decreased to 28% in the last 6 months period with cerebrovascular events increasing to 56%.Conclusion: We found a progressive rise in the proportion of donors with non-traumatic causes of brain death in a 30 months period of time. Considering the same territory of organ procurement; this can be translated to a decrease in number of fatal motor vehicle accidents. The transplant outcome in this regard is under investigation in another study.

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Cite the article

Ebrahimi AP,Tayebi Meybodi K, Hosseini S, Dashti SHA, Jafarian A. Trend of Causes of Brain Death in Liver Graft Donors in Northern Iran; A Shift from Trauma to Cerebrovascular Events in 30 Months. Clin Surg. 2016; 1: 1186.