Journal Basic Info
- Impact Factor: 1.995**
- H-Index: 8
- ISSN: 2474-1647
- DOI: 10.25107/2474-1647
Major Scope
- Minimally Invasive Surgery
- General Surgery
- Emergency Surgery
- Colon and Rectal Surgery
- Bariatric Surgery
- Orthopaedic Surgery
- Vascular Surgery
- Endocrine Surgery
Abstract
Citation: Clin Surg. 2016;1(1):1148.Review Article | Open Access
Management of Overwhelming Postsplenectomy Infection Syndrome
Naoki Hashimoto
*Correspondance to: Naoki Hashimoto
PDF Full Text DOI: 10.25107/2474-1647.1148
Abstract
Overwhelming postsplenectomy infection (OPSI) is a rare medical emergency, mainly caused by encapsulated bacteria, shortly progressing from a mild flulike syndrome to a fulminant, potentially fatal, sepsis. The risk of OPSI is higher in children and in patients with underlying benign or malignant hematological disorders. The identification of Howell-Jolly bodies on peripheral blood examination is an important clue to the diagnosis of asplenia or hyposplenia. Management of these patients includes a combination of immunization, antibiotics prophylaxis. Patient’s education about long-term risk of OPSI and physician’s awareness of a potentially lethal medical emergency are important factor for preventing and management of OPSI.
Keywords
OPSI; Howell-Jolly body; Encapsulated bacteria; Vaccines
Cite the article
Hashimoto N. Management of Overwhelming Postsplenectomy Infection Syndrome. Clin Surg. 2016; 1: 1148.
